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1st Winter On-line School on “Brain Clearance Meets Complex Systems”
14-15 December 2021
Venue: Saratov State University, Saratov, Russia

Alexey Brazhe

Alexey Brazhe

Faculty of Biology, Moscow State University, Moscow, Russia, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

"Links between spatially detailed models of astrocytic Ca2+ activity and interpretation of Ca2+ imaging data"

Astrocytes create an active environment for the networks of neurons, regulating the metabolic characteristics of nerve tissue and modulating synaptic connections. We combine new data on astrocyte morphology with the equations of calcium dynamics in astrocytic processes. To this end, we create realistic patterns of spatial networks based on experimental data and associate them with model equations determined by local cell morphology.

Certificate