Olga N. Berdina

PhD. leading researcher at the laboratory of somnology and neurophysiology of Scientific Centre for Family Health and Human Reproduction Problems, Irkutsk

It’s well known, that sleep is as important for good health as diet and exercise. It is particularly important for children and adolescents as they need to grow and develop. Quality sleep is necessary to ensure the plasticity of the brain, growth and maturation, development and improvement of mental abilities, to prevent some chronic diseases. The aims of our studies are to evaluate macro/micro sleep pattern features in children and adolescents with some diseases such as obesity and sleep apnea as well as their relationships with hormonal and molecular parameters for search any biomarkers and predictors both of somatic pathologies and neurocognitive decline. Our findings suggested a possible functional role of slow wave activity deficit and sleep spindle properties changes in early dysfunction of β-amyloid metabolism as predictor of cognitive impairment.